Acyl group turnover in lipids of rat brain.
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Acyl group turnover in lipids of rat brain. by Fergus J. Doherty

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Published by University of Birmingham in Birmingham .
Written in English


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Thesis (Ph.D)-University of Birmingham, Dept of Biochemistry.

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Open LibraryOL13737866M

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Taken together, these discoveries open up new vistas for research on ethanol effects on brain membrane because acidic lipids seem to be especially important for the function of membrane proteins. Best known is the strong relationship between Na +, K + -ATPase Cited by: 4.   A Brief Synopsis and History of Arabidopsis Acyl-Lipid Metabolism. Perhaps the best overview of plant acyl-lipid synthesis is provided in the textbook chapter by Somerville et al. (), which is expected to be updated in Other more specialized reviews can be found in the Reference section of this chapter, where they are designated with the term “Review” after the by: Coenzyme A and Short-Chain Acyl-CoA Species in Control and Ischemic Rat Brain Article (PDF Available) in Neurochemical Research 27(12) December with . Structured PLs (SPLs) are PLs that can be formed with specific fatty acyl groups in the sn-1 and/or 2 position(s) of PLs through enzymatic acidolysis catalyzed by PLA1, PLA2, and various lipases from bacteria and can be seen in recent studies (Table ), incorporation of specific fatty acids such as CLA, ALA, EPA, and DHA has attracted attention due to their benefits in health.

Unfortunately, the rat brain fatty acid 2-hydroxylase was refractory to purification, and the molecular identity of this enzyme remained elusive. Regardless, Kishimoto’s pioneering work on the rat brain fatty acid 2-hydroxylase provided the foundation for the current knowledge about FA2H (for reviews see Kishimoto et al. () and Hama ()). Enzymic synthesis of 1-alkylacyl-sn-glycerophosphorylethanolamines by the CDP-ethanolamineradylacyl-sn-glycerol ethanolaminephosphotransferase from microsomal fraction of rat brain. J. Lipid Res. –   Acyl lipids in Arabidopsis and all other plants have a myriad of diverse functions. These include providing the core diffusion barrier of the membranes that separates cells and subcellular organelles. This function alone involves more than 10 membrane lipid classes, including the phospholipids, galactolipids, and sphingolipids, and within each class the variations in acyl chain Cited by: Phosphatidylserine or 1,2-diacyl-sn-glycerophospho-L-serine is an important anionic phospholipid, which brings essential physical properties to membranes in both eukaryotes and ndently of this, it has many biological functions in cells, including effects on blood coagulation and apoptosis, and it is the precursor for phosphatidylethanolamine in prokaryotes and in .

Structure. The long-chain bases, sometimes simply known as sphingoid bases, are the first non-transient products of de novo sphingolipid synthesis in both yeast and mammals. These compounds, specifically known as phytosphingosine and dihydrosphingosine (also known as sphinganine, although this term is less common), are mainly C 18 compounds, with somewhat lower levels of C 20 bases.   In cyanobacteria fatty acids destined for lipid synthesis can be synthesized de novo, but also exogenous free fatty acids from the culture medium can be directly incorporated into lipids. Activation of exogenous fatty acids is likely required prior to their utilization. To identify the enzymatic activity responsible for activation we cloned candidate genes from Synechocystis sp. PCC and. Get this from a library! Enzymes of Lipid Metabolism II. [Louis Freysz; Henri Dreyfus; Raphaël Massarelli; Shimon Gatt] -- This book presents the proceedings of the 2nd meeting on "Enzymes of Lipid Metabolism" which took place in Strasbourg in October, It . Nicolas G. Bazan is a neuroscientist and eye researcher, author, educator, mentor, developer, music enthusiast, and art lover. His research focuses on neurodegenerative diseases, aiming to understand endogenous modulation of neuroinflammatory signaling and of cell survival using cellular, molecular, and disease models including lipidomics.